About Us

The Continuous Chemical Systems group is dedicated to utilizing the advantages inherent to flow chemistry to increase both the capabilities of organic chemists and the our understanding of chemical reactivity. One of the main driving forces in our lab is the development of instrumentation to maximize the potential of a given multistep process while minimizing the equipment required and process development between different syntheses. The Chemical Assembly System approach we introduced in 2015 used selective transformations in an interchangeable manner to perform convergent and divergent syntheses to create libraries of compounds bearing different structural cores. This work led to the development of the Radial Synthesizer, which further reduced the complexity of a flow chemical setup by redefining a reaction module as simply the stabilized set of conditions required to perform a controlled chemical reaction. By making these modules equally accessible from a central core, any single or multistep process can be achieved without reconfiguration of the instrument.

For more information about the capabilities of the instrument, please see our recent work (Nature, 2020).

For more information about our work, please visit our webpage (Continuous Chemical Systems Homepage).